Front Cover: A Systematic Review of Metabolic Alterations Underlying IgE‐Mediated Food Allergy in Children

Mol. Nutr. Food Res. 2021, 65, 202100536 DOI: 10.1002/mnfr.202100536 IgE-mediated food allergies (IgE-FA) are considered a growing epidemic. Its pathogenic mechanisms remain however largely unknown. The authors performed literature search followed by in-depth pathway mapping of IgE-FA in children, and revealed shift energy metabolism, next to aberrant metabolization bile acids, lipids, nucleotides, fecal SCFAs amino acids. As such, this work confirmed the unprecedented opportunities metabolomics while offering solid basis for future FA research. This is reported Lynn Vanhaecke co-workers article number 2100536.